HOXD9 Antibody, HRP conjugated

Code CSB-PA010689LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HOXD9 Polyclonal antibody
Uniprot No.
Target Names
HOXD9
Alternative Names
homeobox D9 antibody; Homeobox protein Hox D9 antibody; Homeobox protein Hox-4C antibody; Homeobox protein Hox-5.2 antibody; Homeobox protein Hox-D9 antibody; Hox 4.3 antibody; Hox 5.2 antibody; HOX4 antibody; HOX4C antibody; HOXD9 antibody; HXD9_HUMAN antibody; RP23 313J15.10 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Homeobox protein Hox-D9 protein (38-276AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Gene References into Functions
  1. HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma PMID: 26514226
  2. HoxD9 expression is regulated by histone acetylation in endothelial progenitor cells PMID: 25826494
  3. Data show that overexpressing homeobox D9 protein HOXD9 in mucinous ovarian carcinomas (MOCs)cells augmented the neoplastic phenotype PMID: 26075790
  4. The study investigates the temperature dependence of the internal motions of the lysine side-chain NH3(+) groups that form ion pairs with DNA phosphate groups in the HoxD9 homeodomain-DNA complex. PMID: 25489884
  5. Results show that melanoma patients with HOXD9 hypermethylation in lymph node metastasis had poorer disease-free and overall survival. PMID: 24014427
  6. A genome-wide array-comparative genomic hybridization (aCGH) analysis revealed global chromosomal aberration in MWCNTs-treated clones, predominantly at chromosome 2q31-32, where the potential oncogenes HOXD9 and HOXD13 are located PMID: 23984819
  7. The association between SNP of the HOXD9 gene and developmental hip dysplasia reached significance in Chinese Han females. PMID: 22520331
  8. Our results suggest that HOXD9 may be a novel marker of GCSCs and cell proliferation and/or survival factor in gliomas and glioma cancer stem-like cells, and a potential therapeutic target. PMID: 21600039
  9. 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly PMID: 11778160
  10. findings not only indicate that the HOXD9 gene is exclusively expressed in the rheumatoid arthritis synovium but also suggest that the HOXD9 gene contributes to the pathology of rheumatoid arthritis through the fibroblast-like synoviocytes PMID: 12060849
  11. HoxD9 and Pbx1 are inappropriately expressed in most human esophageal squamous cell carcinoma. Understanding the role of Hox genes in esophageal epithelial cell carcinogenesis may not only augment early detection but also offer possiblde treatment. PMID: 15770739

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Subcellular Location
Nucleus.
Protein Families
Abd-B homeobox family
Database Links

HGNC: 5140

OMIM: 142982

KEGG: hsa:3235

STRING: 9606.ENSP00000249499

UniGene: Hs.236646

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